Do side missions matter in Mass Effect 2? Many missions and side quests are presented as completely optional, but not if players want to achieve the best ending. Recruitment and Loyalty missions in Mass Effect 2 have a massive impact on how players can experience that game and its sequel, and potentially Mass Effect 4, if they import their save.
Does Mass Effect 2 have an endgame? Three elements factor into how Mass Effect 2’s endgame shakes out: Normandy ship upgrades, the decisions you make about which crewmates you assign to essential tasks during the final mission, and whether each member of your crew is considered “loyal” to Shepard.
What missions should I do before Reaper IFF? Do literally everything you’re gonna do before the IFF. You only get one mission after, and that’s best gonna be spent on legion’s loyalty mission as it’s the only time you can do it. I would do overlord in act 1 when you are getting the first set of dossiers.
Can you do all loyalty missions Mass Effect 2? Yes, it’s possible. You need to finish all loyalty missions (except for Legion’s) before going to the derelict Reaper.